As long as we take a reasonable man approach to this I can think of nothing whereby we would be better off weighing more. I usually carry about one half tank of water and after the initial burn down, tend to run between 1/4 -3/4 tank of fuel. Bt the same token, I bet most of us don't run around with full waste tanks. I have slowly been reducing the amount of tools and spare parts I carry. If I could get Dragon Lady to reduce the stuff she carries I would be all set. (I weighed it before and after:1500 lbs delta.)
As a reasonable man, I as of yet see no reason to reduce the amount of the Gin reserve. Malaria must be fought when and where ever you find it.
Come to think of it, I probably need to lose 100lb to get to fighting weight and thus help out bus max gross.
We motorcylists are usually wondering about the best way to improve performance. Nothing dramatically increases performance as much as a lighter rider: Greater percentage of total weight.